Image source: Telegraph.co.uk
As we grow old, out natural capacity of the tooth also decreases. Sometimes, this leads to replacement of teeth. In that case, inorganic cements based on calcium or silicon-based mineral aggregates are filled. But often the cement fails to give that much normal mineral volume which is necessary in the gum. Also they often get infected resulting in more problems for the patient.
In case of a problem due to infection – using cements or fillings often lead to infections – which complicate the problem. If the infection is big then dentists finally extract the tooth out of the mouth.
So, scientists have now come forward with a natural solution. They have now found the innovative way of natural formation of reparative dentine by mobilization of stem cells in the tooth pulp.
The process involves delivering low dosage of glycogen synthase kinase (GSK-3) antagonists through collagen sponges that promote the restoration of dentine. After a few days, the sponge is degraded leading to replacement of complete and effective natural repair. It could do wonder in the field of dental science.
New Research on Dentine at King’s College
A team of researchers at King’s College in London has found another method of stimulating the renewal of living stem cells in tooth pulp through Alzheimer’s drug. Due to infection, the inner pulp of tooth can get infected. In order to prevent so, a thin band of dentine is applied to the tooth pulp to disinfect and seal the same. But sometime this remains far from satisfactory and requires more innovative and appropriate dental implant to correct the same.
A feature published in scientific reports stated that researchers from the Dental Institute at King’s College, London, have found a new remedy with stimulation of stem cells located within the pulp of the tooth to generate new dentine. It reduces the dependence upon external substance and methods like filings or cements.
Professor Paul Sharpe from King’s College London stated, “The simplicity of our approach makes it ideal as a clinical dental product for the natural treatment of large cavities, by providing both pulp protection and restoring dentine. In addition, using a drug that has already been tested in clinical trials for Alzheimer’s disease provides a real opportunity to get this dental treatment quickly into clinics, he added further.
Experts feel this is an exhaustive process. It will help to enhance the natural repairing ability of the teeth in regard to large cavities. The stimulation of the renewal of the stem cells will include Tideglusib (Substance) which is also useful to cure Alzheimer’s disease. Hope this new invention will help people get their dental implant done in a more natural and safer way.